The labchip gx is classified as a class 1 device because the lasers are appropriately enclosed embedded and indicated with warning labels. Labchip gxii touch protein characterization system perkinelmer. The labchip gxii touch protein characterization system provides the complete. Increase efficiency and accelerate protein workflows with the labchip gxii. Improving characterization of monoclonal antibodies. The labchip gx rna assay analysis determines the quality of the rna sample by measuring the relative amounts of know rna fragments relative to the total rna present in the sample. The gxii touch system helps to accelerate the development of biotherapeutic drugs by automating the protein characterization process. Ongoing analytical measurement of nutritional additives and the total micronutrient content in the cereal is one way in which food producers can quantify the quality and consistency of their cereal products. The labchip gx touch gxii touch are classified as a class 1 device because the lasers are appropriately enclosed embedded and indicated with warning labels. Perkinelmer launches labchip gx touch and gxii touchtm.
The labchip gxii touch protein characterization system provides the complete solution for reproducible quantitation, molecular weight sizing and percent purity analysis of protein samples. White paper streamlining materials innovation processes with electronic lab notebook eln and data analytics for optimum efficiency. Rapid analysis of nglycans on the labchip gxii microchipce platform abstract a high throughput microchipce method on the labchip gxii has been developed for profiling nglycans from recombinant igg antibodies. Touch protein characterization system and assays for doe development to. Labchip gx touch nucleic acid analyzer dna and rna quantitation and sizing can be done in seconds using automated capillary electrophoresis separation. The files used by the ice cfr software are created using a file format unique to the software. In the field of vaccines and biologics, the labchip gxii has been widely adopted across the discovery and development pipeline by a large number of pharmaceutical and vaccine developers to improve. Contact the perkinelmer center for training and development for information.
Both systems combine calipers assay technology with advanced data analysis and visualization software. Pe labchip gx touch ht dnarna characterization system. Caliper life sciences introduces labchip gx and gxii. After the labchip instrument optics detect the laserinduced fluorescent signal, easy to use system software automatically analyzes the data and provides the user. Labchip gxii touch ht protein characterization system. This approach can lead to the development of robust. Labchip gxii touch biotherapeutics how a chip works. The software contains an application security module for user account management and for access of controls to. Discover the effortless versatility of an instrument that makes it easy to handle any sample matrix, any interference, and any particle size. Labchip gxii touch protein characterization system. From our original factory warranty through a comprehensive line of customer support plans, perkinelmer offers you field service engineers and inhouse specialists who are. Automated electrophoresis for protein characterization figure 1.
Protein detection and quantification is required for the development of proteinbased therapeutics, as well as research into cell signaling, growth factors, and a variety of disease states. Caliper gx ii system application evaluation perkinelmer yumpu. Labchip gxii touch ht protein characterization system perkinelmer. For example, automating the characterization process allows multiple, critical quality attributes to be obtained significantly faster. Use the links below to quickly find your software solution download. With our preverified assays, there is no or little method development needed. The labchip gx touch nucleic acid analyzers microfluidic technology generates reproducible.
This paper explores the numerous challenges materials scientists and engineers face, from the time it takes to bring new materials to market to the difficulties delivering suitable formulations and testing against specified criteria, and how. Pe labchip gx touch ht dnarna characterization systemyear 2016. Rapid analysis of nglycans on the labchip gxii microchip. The labchip gx system can enhance genomics research process by precisely quantifying nucleic acids. Protein sizing and quantification on a microchip is achieved by integration of the sample 3,4 automatic sampling directly from a 96 or 384well microtiter plate software 21cfr part 11 determines the size, quantification, and purity. The system can be located in a designated laboratory room to limit system access to authorized individuals 21 cfr 11. A high throughput capillary electrophoresis method to. Electrophoresis separation for high sensitivity dnarna analysis. Run up to 400 samples with 4 primes for sample batch sizes up to 96 or 8 primes for sample batch sizes of 48 samples or fewer. Caliper gx ii system application evaluation perkinelmer. Protein purification automated small scale purification. Automated electrophoresis for protein characterization. Labchip gxii for high throughput characterization of.
Both systems combine calipers highly reproducible assay technology with advanced data analysis and visualization software. The file types created by the ice cfr software have the extensions icf, cal, dat, bch, ief and itf. It allows the complete assessment of rna quality for better gene expression data. The labchip gxgxii electrophoresis systems use a single sipper microfluidic chip to aspirate samples directly from 96 or 384well plates. The high resolution labchip is designed to be compatible with the glycan screening assay and low molecular weight protein assay on the labchip gxii microfluidic capillary electrophoresis cesds platform. A caliper labchip gxgxii instrument with labchip gxp software is a closed system 21 cfr 11. Perkinelmer solutions for accelerated biotherapeutic process development automation automated small scale purification of biotherapeutic proteins labchip gxii touch automated electrophoretic separations of rna, dna, proteins and glycans labchip ds high throughput microfluidic uvvis for research use only.
With 96well and 384well plate compatibility and the ability to select single wells at any location in a plate, the labchip gx and gxii systems provide researchers with unmatched throughput, flexibility, and performance. Lapchip gxii touch protein assay protfolio mediray. Product service and customer support plans perkinelmer offers a full range of services to ensure your success. The labchip gx is designed for both rna and dna analysis, while the labchip gxii runs rna, dna, and also protein assays. High resolution labchip gxii, touch ht perkinelmer. Selexis sa, 14 chemin des aulx, ch1228 plan les ouates. Whether it is quantitating monoclonal antibody titers, optimizing protein expression conditions, or rapidly screening igg nglycan profiles, the labchip gxii is the perfect benchtop tool to. With 96well and 384well plate compatibility and the ability to select single wells at any location in a plate, the labchip gx and gxii systems provide researchers with flexibility and performance. Improving the efficiency of metagenomic analysis of stool samples 2018 automated ngs library preparation with covaris focusedultrasonicator workflow solution 2018. The labchip gxii touch protein characterization system offers an automated alternative to traditional methods by streamlining slab gel electrophoresis, while also providing the increased throughput and data quality required by biotherapeutics and genomics workflows. The instrument optics detect samples by laserinduced fluorescence.
Our biotherapeutics research products are designed for consistent and reproducible results, and are a component of glpcompliant processes in the worlds leading pharmaceutical, biotechnology and contract research organizations. Labchip gxii touch biotherapeutics how a chip works youtube. There was a 4 log linear range of detection lower limit of detection was about 10 pg. The labchip gx touch nucleic acid analyzers microfluidic technology generates reproducible, highresolution data and is optimal for. The labchip gx is the most accurate and advanced nucleic acid separations system available. Increase efficiency and accelerate protein workflows with. Application note analysis of pb, dc, and as in spice mixtures with an inherent toxicity, a tendency to accumulate in the food chain and a particularly low removal rate through excretion, lead pb, cadmium cd and arsenic as cause harm to humans even at low concentrations. Leveraging microfluidic electrophoretic separation technology, the labchip gxii touch system enables rapid characterization with minimal sample preparation setup and sample input volume. The labchip gxp security software provides users with with electronic signature, electronic record retention, and access management to streamline meeting requirements for compliance. Labchip small rna assay perkinelmer applied genomics. It provides a fast, economically efficient means to assess the main glycoforms of igg and related proteins. When powered on, the chip, eject, and status indicators labchip gxii light up.
Perkinelmer analytical solutions for accelerated process development. Analysis of each sample is fast, occurring in 40 sec, and the samples are analyzed directly from a 96well plate. In this method pngase freleased nglycans in a 96well microtiter plate are fluores. The leader in this field is caliper lifescience, recently acquired by perkinelmer. Labchip gx is a program that provides support for the high sensitivity dnarna analysis, dna smear analysis, rna and gdna integrity analysis. Labchip gx touch nucleic acid analyzer perkinelmer. Import labchip gx or labchip 90 data files with ease. Credit card and paypal payments are accepted, but may be.
Perkinelmer has led the way for over 25 years with powerful software and informatics solutions. Labchip gxii separation is based on size, with the resolution ranging from 14 to 300 kda. Read perkinelmers applied genomics blog to learn how to improve the efficiency of your work in the applied genomics field. Our protein detection assays allow you to optimize performance, simplify workflows, and increase throughput. The labchip gxii touch protein characterization system offers an automated alternative to traditional methods by streamlining slab gel electrophoresis, while also providing the increased throughput and data quality required by biotherapeutics and genomics. Caliper labchi p gx instruments contain class 3b laser diodes. Like its predecessor the labchip90, the gx suite of instruments utilizes perkinelmers innovative microfluidics technology to perform reproducible, highresolution, eletrophoretic separations. Biotherapeutics allow researchers to explore new mechanisms for the treatment of a variety of conditions. The labchip gxgxii systems offer researchers an automated alternative by streamlining the multiple, manual steps of slab gel electrophoresis, while also providing the throughput and data quality. Right click on the link to the file and choose save target as and save the zip file to your desktop.
Blabchip gx touch gxii touch user manual perkinelmer, inc. Purchase orders, checks, and wire transfers are preferred. The glycan screening reagent kit is designed for the labchip gxii, labchip gxii touch ht and labchip gxii touch 24 microfluidic systems. The information in this section is from caliper labchip gxgx ii user manual how the caliper software analyzes rna data. The labchip gxii is a complete solution for consistent and precise analysis of protein samples, and is an ideal instrument for protein research users. The caliper life sciences labchip gxii system delivers quantitative, highthroughput protein analysis necessary to truly accelerate these development work flows. Labchip gx touch nucleic acid analyzer perkinelmer applied. After connecting a pc and opening the labchip software the status indicator. The computer supplied with the labchip gx instrument has internal. Microfludic on a chip offers new areas of development and bioterapeutic studies. Proteinsimple ice cfr software is used for system control, data acquisition and collection of critical audit information. Additionally, it provides data in the tabular form, which can then be analyzed or easily exported into a spreadsheet format. Labchip gx gxii touch instruments contain class 3b laser diodes.
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